Fabrication of Zn2+-Loaded Polydopamine Coatings on Magnesium Alloy Surfaces to Enhance Corrosion Resistance and Biocompatibility

In this study, inspired by the adhesion protein of mussels, a Zn2+-loaded polydopamine (PDA/Zn2+) coating was prepared on an alkali–heat-treated magnesium alloy surface, through chelating effect PDA with metal ions, to improve anticorrosion and biocompatibility. The results water contact angles show that PDA/Zn2+ coatings different Zn2+ contents had excellent wettability, which contributed selective promotion albumin adsorption. corrosion degradation behaviors modified alloys were characterized using potentiodynamic scanning polarization curves, electrochemical impedance spectroscopy (EIS), immersion test, indicate significantly improved increase content in coating. Meanwhile, concentrations demonstrated hemocompatibility, confirmed assays hemolysis rate platelet behaviors. addition, regarding growth endothelial cells (ECs) suggest that, due sustained release from coatings, could enhance adhesion, proliferation, upregulated expression vascular factor (VEGF) nitric oxide (NO) cells, better cytocompatibility ECs be achieved as concentration increased. Therefore, developed study utilized modify surfaces, simultaneously impart anticorrosion, endothelialization.